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Substantial case rate increases were recorded among unvaccinated and vaccinated persons when Omicron became the predominant variant in December, resulting in decreased IRRs and declining crude VE estimates (7). The SARS-CoV-2 B.1.1.529 (Omicron) variant emerged in the United States during December 2021 (6) and by December 25 accounted for 72% of sequenced lineages (7). Department of Health and Human Services. MMWR Morb Mortal Wkly Rep 2021;70:128490. On November 19, 2021, and November 29, 2021, CDC expanded recommendations for booster doses to include all adults aged 18 years. NJ has among lowest gun ownership in U.S. Gov. The ratio of hospitalizations to cases was moderately lower among fully vaccinated (13.1 hospitalizations per 100 cases) compared with unvaccinated (19.0 hospitalizations per 100 cases) groups. Monitoring incidence of COVID-19 cases, hospitalizations, and deaths, by vaccination status13 US jurisdictions, April 4July 17, 2021. COVID-19-Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status - COVID-NET, 14 States, July 2021-January 2022. To get unlimited access to the latest news about the pandemic's impact on New Jersey, please subscribe or activate your digital account today. New variants combined with a reduction in masking and other non-pharmaceutical interventions may also lead to more transmission, which can in turn lead to more deaths. Townhall weekly columnist. According to the CDC website, COVID-19 case and death information is collected from jurisdictions that can link their case surveillance data to immunization data, and identify the vaccination status of people who test positive. For deaths, a single week (November 28December 4, 2021) of data was reported during the December 2021 period of Omicron emergence, but the proportion of Omicron variant during that first week was approximately 1%. The overall fully vaccinated group includes FDA-approved vaccinations of unknown vaccine type. Although the data we use in this analysis are not broken out by time since last vaccination, given the plateauing vaccination rate, it is likely that many of the vaccinated people who died of COVID-19 had the primary series or a booster many months or even over a year earlier, meaning they were less protected against severe illness than they once were. Email sent to FactCheck.org. medRxiv. Similar trends were noted for differences in the mortality rates among these three groups (0.1, 0.6, and 7.8 per 100,000 population, respectively) during OctoberNovember. COVID-19 is on track to be the third leading cause of death in 2022, for the third year in a row, and this year, about half of those deaths over the course of the year were among people who had at least their primary series. Abbreviations: FDA=Food and Drug Administration; IRR=incidence rate ratio; NC = not calculated for categories with counts <20; NR=not relevant for individual vaccine types because the comparison being made is to overall unvaccinated counts and age-adjusted rates. Average weekly, age-standardized rates of cases and deaths (events per 100,000 population) were higher during periods of Delta predominance and Omicron emergence than during pre-Delta and Delta emergence periods and were consistently higher in all periods among unvaccinated persons (range=64.0725.6 [cases] and 1.511.4 [deaths]) than among fully vaccinated persons (range=7.4230.9 and 0.10.7). With more than a dozen dead whales, Gov. Indeed, vaccinated people now make up the majority of the population 79% of adults have completed at least the primary series and the latest CDC data show that vaccinated people also now represent the majority of COVID-19 deaths. Eligible persons should stay up to date with COVID-19 vaccinations. ** A COVID-19associated death occurred in a person with a documented COVID-19 diagnosis who died, and whose report local health authorities reviewed (e.g., using vital records, public health investigation, or other data sources) to make that determination. The fall in the share of deaths that are among unvaccinated people could also be explained by changes in the unvaccinated population. He said everyone should understand the overwhelming number of New Jersey residents contracting the virus, going to the hospital because of a COVID-related illness, or dying from complications of COVID continue to be folks who are either unvaccinated, or under-vaccinated. MMWR Morb Mortal Wkly Rep. 2022 Jan 28;71(4):125-131. doi: 10.15585/mmwr.mm7104e1. MMWR Morb Mortal Wkly Rep 2022;71:132138. For primary mRNA vaccination series, the vaccine product of the second dose was used to determine primary series product type. When the Omicron variant emerged during December 2021, case IRRs decreased to 4.9 for fully vaccinated persons with booster doses and 2.8 for those without booster doses, relative to OctoberNovember 2021. A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. They were eight times more likely to be hospitalized with COVID-19 than fully vaccinated people without a booster. 113,254 hospitalizations with COVID-19 among . Booster doses provided the largest gains in protection among persons aged 65 years followed by persons aged 5064 years when compared with those aged 1849 years. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. The share of COVID-19 hospitalizations by vaccination status in Cosmos data is consistent with a recent CDC MMWR study of 13 jurisdictions, which similarly found fully vaccinated people were 14% of COVID-19 hospitalizations in the June-July period. SARS-CoV-2 B.1.1.529 (Omicron) variantUnited States, December 18, 2021. According to CDC, people ages 12 and older who have had a bivalent booster shot have a 15 times lower risk of death than an unvaccinated person. The state has requested10 strike teams of 15 members each, said Col. Patrick Callahan, superintendent of the state police. SAS (version 9.4; SAS Institute) and R (version 4.1.0; R Foundation) were used to conduct all analyses. Excluded were partially vaccinated persons who had received at least one FDA-authorized or approved vaccine dose but did not complete a primary series 14 days before collection of a specimen with SARS-CoV-2 RNA or antigen detected. To interpret IRR changes, age-standardized crude vaccine effectiveness (VE) was estimated as (1 [incidence in vaccinated / incidence in unvaccinated]). Ascertaining vaccination status for COVID-19 patients through active linkage of case surveillance and immunization information systems typically assumes that cases among persons who are unmatched to the registry are unvaccinated. NJ seeks reinforcements to help hospital staff depleted by COVID. and are much worse at preventing infection or mild disease. -. During OctoberNovember, age-standardized IRRs for deaths among unvaccinated persons were 53.2 compared with those in fully vaccinated persons with a booster dose and 12.7 compared with persons without a booster dose; these results represented crude VE against death of 98% and 92%, respectively. Key Points. Posted August 29, 2021. doi: 10.1101 . Proportion of Adults in the COVID-19Associated Hospitalization Surveillance Network (COVID-NET) Catchment Area and, Figure 2.. The Henry J. Kaiser Family Foundation Headquarters: 185 Berry St., Suite 2000, San Francisco, CA 94107 | Phone 650-854-9400 This decline suggests a change in crude VE for infection from 93% during AprilMay, to 89% during June, 80% during JulyNovember, and to 68% during December. The numbers are over the past 30 days: Scott Fallon has covered the COVID-19 pandemic since its onset in March 2020. Exposures: Symptoms are milder and shorter-lived in vaccinated people. Vaccine effectiveness of primary series and booster doses against Omicron variant COVID-19associated hospitalization in the United States. Peaks in age-standardized case and death rates occurred during August (>95% of infections attributed to the Delta variant); case rates also peaked during the 2 weeks ending December 18 and 25 (39% and 72% infections attributed to the Omicron variant, respectively) (Figure). Josh Michaud Follow @joshmich on Twitter SARS-CoV-2 Vaccination and Clinical Presentation of COVID-19 in Patients Hospitalized during the Delta- and Omicron-Predominant Periods. Per capita COVID-19 case rates in boosted, fully vaccinated, and unvaccinated populations in Massachusetts Sep 05 Sep 19 Oct 03 Oct 17 Oct 31 Nov 14 Nov 28 0 250 500 750 1,000 1,250 Per capita COVID cases for individuals 12+ years of age (August 29, 2021 -December 4, 2021) Source: MA DPH Unvaccinated Fully Vaccinated & not Boosted Boosted 1. The claim: Death rate among COVID-19 vaccinated people is significantly higher compared with unvaccinated population. Last updated 17 Mar 2022. ** Reporting is by primary series vaccine type rather than additional or booster dose vaccine type. During the most recent coronavirus update on Monday, Gov. Dr Anderson reported grants from Pfizer, Sanofi, GSK, Janssen, MedImmune, Regeneron, PaxVax, Micron, and Merck as well as personal fees from Moderna, Pfizer, Sanofi, GSK, Janssen, Medscape, Kentucky BioProcessing Inc, and WCG and ACI outside the submitted work; additionally, his institution has also received funding from the National Institutes of Health to conduct clinical trials of COVID-19 vaccines. The added benefits of booster doses were especially prominent among persons aged 5064 and 65 years. During OctoberNovember, unvaccinated persons had 13.9 and 53.2 times the risks for infection and COVID-19associated death, respectively, compared with fully vaccinated persons who received booster doses, and 4.0 and 12.7 times the risks compared with fully vaccinated persons without booster doses. DOI: http://dx.doi.org/10.15585/mmwr.mm7104e2. COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence - 25 U.S. Jurisdictions, April 4-December 25, 2021. Fully vaccinated COVID-19 hospital patients had an aOR of 0.33 for death or the need for invasive mechanical ventilation. Vaccinated and unvaccinated patient characteristics were compared in a representative sample with detailed medical record review; unweighted case counts and weighted percentages were calculated. So vaccination reduces the ICU risk by 93.2 percent. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. However, the post claims that the death rate for vaccinated people is greater than the death rate . Johnson AG, Amin AB, Ali AR, Hoots B, Cadwell BL, Arora S, Avoundjian T, Awofeso AO, Barnes J, Bayoumi NS, Busen K, Chang C, Cima M, Crockett M, Cronquist A, Davidson S, Davis E, Delgadillo J, Dorabawila V, Drenzek C, Eisenstein L, Fast HE, Gent A, Hand J, Hoefer D, Holtzman C, Jara A, Jones A, Kamal-Ahmed I, Kangas S, Kanishka F, Kaur R, Khan S, King J, Kirkendall S, Klioueva A, Kocharian A, Kwon FY, Logan J, Lyons BC, Lyons S, May A, McCormick D; MSHI; Mendoza E, Milroy L, O'Donnell A, Pike M, Pogosjans S, Saupe A, Sell J, Smith E, Sosin DM, Stanislawski E, Steele MK, Stephenson M, Stout A, Strand K, Tilakaratne BP, Turner K, Vest H, Warner S, Wiedeman C, Zaldivar A, Silk BJ, Scobie HM. Drs Billing and Shiltz reported grants from the Council of State and Territorial Epidemiologists (CTSTE) and the CDC Dr Schaffner reported grants from CDC during the conduct of the study as well as personal fees from VBI Vaccines outside the submitted work. * Events per 100,000 population. Questions or messages regarding errors in formatting should be addressed to Although COVID-19 vaccine effectiveness decreased with emergence of the Delta variant and waning of vaccine-induced immunity, protection against hospitalization and death has remained high. Sect. ** 95% CIs were calculated after detrending underlying linear changes in weekly incidence rates using piecewise linear regression. Murphy said 99.99% of the 32,000 COVID-19 hospitalizations between Jan. 19 and July 12 were unvaccinated individuals. Second, this ecological study lacked multivariable adjustments, and causality could not be determined. Similarly, to be counted as having a booster, a person must be at least two weeks out from their booster or additional dose before testing positive. Phil Murphy. Marianne Guenot. The waning protection from vaccines is why CDC recommends recent booster shots, and why its especially important for people at higher risk to stay up-to-date on boosters. Last updated 24 Mar 2022. On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings (https://www.cdc.gov/media/releases/2021/p0924-booster-recommendations-.html). Conflict of Interest Disclosures: Drs Yousey-Hindes, Lynfield, Sutton, Talbot, and Meek reported grants from US Centers for Disease Control and Prevention (CDC) during the conduct of the study. MMWR Morb Mortal Wkly Rep 2021;70:17314. Data for CDCs COVID Data Tracker site on Rates of COVID-19 Cases and Deaths by Vaccination Status. Internet bloggers: "Fully vaccinated Australians in hospital for COVID-19 surpass unvaccinated" PolitiFact's ruling: Half True Here's why: Australia faces a surge of COVID-19 cases as the highly contagious omicron COVID-19 variant continues to spread across the continent. Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status. Some 73.3% of hospitalized COVID patients are unvaccinated; 23.7% are fully vaccinated; and 3% are partially vaccinated. The age-standardized IRR for cases in unvaccinated versus fully vaccinated persons was 13.9 during AprilMay and progressively declined to 8.7 during June, 5.1 during JulyNovember, and 3.1 during December, coinciding with the periods of Delta emergence, Delta predominance, and Omicron emergence, respectively. 1:34. Against omicron, however, the vaccines havent. Laboratory-confirmed COVID-19-associated hospitalization, defined as a positive SARS-CoV-2 test result within 14 days before or during hospitalization. [A]lthough rooted in the contention that the agency isnt being nearly as straightforward or transparent or comprehensive as they need to be, my tweet could be interpreted as misleading and thats the absolute last thing I want to do so Ive removed it, he wrote.