venofer dosing calculator

iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. The recipient will receive more details and instructions to access this offer. Below the form there are further instructions on how to use the calculator. The dosage of Venofer is expressed in mg of elemental iron. Avoid or Use Alternate Drug. DICP. 2012;2(4):288-335. VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . Mean change in Hgb from baseline to Week 5 2,5 David McAuley, Pharm.D. Use Caution/Monitor. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Modify Therapy/Monitor Closely. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. 2 *Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with CKD. Jacobs P, Dommisse J. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Applies only to oral form of both agents. 3) Bayraktar UD, Bayraktar S. (2010) Treatment of iron deficiency anemia associated with gastrointestinal tract diseases. There is no resource limitation, as if the tool was hosted on your site, so all your users can make use of it 24/7; The necessary tool updates will take place in real time with no effort on your end; A single click install to embed it into your pages, whenever you need to use it. Applies only to oral form of both agents. Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. All Rights Reserved. *Administer early during the dialysis session. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Finally, a 400-mg dose by 2-hour infusion was examined in 35 patients, but 2 patients experienced such symptoms as hypotension, nausea, and lower back pain. Most adults require a cumulative dose of elemental iron of at least 1 g. Iron replenishment is usually doneintravenously, via iron-dextran, iron sucrose or iron carboxymaltose. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. commonly, these are "non-preferred" brand drugs. ------------------------------------------------------------------------- Iron Dextran Complex [ Infed ] Elemental iron: 50 mg of elemental iron per mL [2 mL] [package insert] BOXED WARNING: WARNING: RISK FOR ANAPHYLACTIC-TYPE REACTIONS Anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session [see How Supplied/Storage and Handling (16.2).] Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Excessive therapy with parenteral iron can lead to excess storage of iron with the possibility of iatrogenic hemosiderosis. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. Minor/Significance Unknown. Minor/Significance Unknown. Since this is less than the threshold of total dose of 20 mg/kg, the deficit can be eliminated with a single infusion. Assure stable intravenous access to avoid extravasation. Divide the calculated dose by the patient's weight (IBW if BMI >30, or actual body weight (ABW) if BMI30) to ensure it does NOT exceed 20mg/kg. Treatment of anemia due to iron deficiency. 1. Monitor Closely (1)iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. No additional iron to replenish stores. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Creating an account is free and takes less than 1 minute. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. Reference www.medicines.org.uk Background Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Separate by at least 4 hours. FERAHEME met the predefined criteria for non-inferiority to Venofer . Iron Sucrose [ Venofer ] Elemental iron: 20 mg/mL (2.5 mL, 5 mL, 10 mL) Solution, Intravenous [preservative free]: [package insert] INDICATIONS: Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD). Minor/Significance Unknown. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . Dose. aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Venofer may reduce the absorption of concomitantly administered oral iron preparations. however iron sucrose requires multiple small intermittent doses over days to weeks. You may need extra iron because of blood loss during kidney dialysis. Human studies not conducted. Found in multiple references. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. Canada residents can call a provincial poison control center. Medicinal forms Avoid or Use Alternate Drug. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Administer on 5 different occasions over a 14 day period. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. Case G. Maintaining iron balance with total-dose infusion of intravenous iron dextran. Avoid or Use Alternate Drug. No data are available regarding overdosage of Venofer in humans. Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. This drug is available at a higher level co-pay. Applies only to oral form of both agents. Always ask your health care professional for complete information about this product and your specific health needs. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. . View the formulary and any restrictions for each plan. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. It is unlikely . Applies only to oral form of both agents. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Other indications for IV are pregnancy iron deficiency, chronic renal impairment or need for rapid repletion. iron sucrose decreases levels of deferiprone by enhancing GI absorption. Applies only to oral form of both agents. Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. Monitor for signs and symptoms of hypotension following each Feraheme infusion. Anemias. You can further save the PDF or print it. Compare formulary status to other drugs in the same class. Applies only to oral form of both agents. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. Kumpf VJ. MDCalc loves calculator creators researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. Human studies not conducted. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Iron stores 500 mg for body weight greater than or equal to 35 kg (77 lbs) and 15 mg/kg for body weight less than 35 kg. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. DOSAGE AND ADMINISTRATION: Venofer must only be administered intravenously either by slow injection or by infusion. Use Caution/Monitor. Applies only to oral form of both agents. Ren Fail. By clicking send, you acknowledge that you have permission to email the recipient with this information. Otherwise, call a poison control center right away. The dosage of Venofer is expressed in mg of elemental iron. The initial hemoglobin rise is more rapid with parenteral iron but on the long term (12 weeks), both therapies reach similar levels of hemoglobin. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. Prior to and at regular intervals during parenteral iron therapy, evaluate serum iron, hemoglobin, and hematocrit. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. iron sucrose, captopril. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. ONE DOSE. Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. Applies only to oral form of both agents. Adults and Children over 15 kg (33 lbs): Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW), Desired Hb = the target Hb in g/dl. Each mL contains 20 mg of elemental iron. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Use Caution/Monitor. Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. There are three fields in the parenteral iron replacement for iron deficiency anemia calculator: Weight can be input in either lbs or kilograms and the required transformations are performed by the calculator.